How Cigarette Smoking Causes Disease and Amputation of Fingertips Arms and legs

Cigarette smoking itself is not habit forming, but it accounts for releasing dopamine, a neurotransmitter associated with , บุหรี่ไฟฟ้า pleasure and reinforcements in the brain, thus causing habit forming tendencies in humans. Cigarette smoking is a chemical found in tobacco leaf, the main ingredient in smoking cigarettes and is asked cause addiction and disease in cigarette smokers, (World Health Organization (WHO)).

Cigarette smoking mimics the actions of acetylcholine, a naturally occurring neurotransmitter in the central nervous system and the nerve-muscle junction of skeletal muscles. Acetylcholine accounts for excitability, that can cause increase heart rate, alertness, and reaction times, (Psychopharmacology (Berl). 1989; 97(2): 257-61. ). Because acetylcholine and cigarette smoking are chemically similar, they trigger the same cholinergic receptors in the brain. The nicotine-acetylcholine receptors consist of lack of feeling endings that release dopamine when coupled or bind with cigarette smoking or acetylcholine. Receptors are like k-cups having the exact dimensions that will fit a neurotransmitter molecule, such as acetylcholine.

The cup itself is repleat with lack of feeling endings (tips of neurons). It is these lack of feeling endings that release dopamine when the neurotransmitter acetylcholine binds with the cup-like acetylcholine receptors (cholinergic receptors). A reinforcing and reward phenomenon of dopamine develops because the dopamine that is released from the lack of feeling endings triggers a feeling of pleasure in the peoples brain. The encouragement mechanism is initiated when the brain becomes enslaved by the pleasure caused by the dopamine that is released from the cholinergic receptors. This means that serotonin levels is constantly seeking to be pleasured. So, and what will happen in the case of cigarette smokers is that they’re going to continue to smoke a pipe so the cigarette smoking from the cigarette can induce the release of dopamine in the brain, causing them to feel happy every time they smoke a cigarette, (Nature Reviews Neuroscience 7, 967-975 (December 2006)).

The first time cigarette smokers smoked cigarettes smoking cigarettes there were only a few cholinergic receptors available because the natural action of acetylcholine only needs the normal amount of receptors offered by nature to do its job. However, the increase concentration of cigarette smoking available caused the normal amounts of cholinergic receptors to become desensitized to the presence of the increased number of cigarette smoking in the cholinergic receptors. This desensitization causes the production or growth and development of more cholinergic receptors. These extra cholinergic receptors will soon become desensitized from the excess cigarette smoking available. Such processes occur until harmony is reached. Harmony is reached when cigarette smokers decide on the amount of smoking cigarettes they will consume or smoke in a given day. At this time, a fixed amount of receptors will be available for the being addicted continue. Smokers will normally say they smoke one or two packages per day. They said so because of the amount of receptors available to accommodate two packages of smoking cigarettes in a day.

A detrimental effect of all this is the fact that such large amounts of cholinergic receptors are now available and famished for cigarette smoking. So, they can stimulate dopamine to pleasure the cigarette smoker. It is why cigarette smokers employ a difficult time quitting. The best approach therefore for a cigarette smoker to use in quitting is to gradually cut back on the amount of smoking cigarettes smoked cigarettes in a given time interval.

In addition to the dopamine-inducing effect of cigarette smoking, is the speeding-up of the heart rate by cigarette smoking whenever a cigarette is smoked cigarettes. From a medical perspective, constantly having an artificial increase in heart rate isn’t recommended either. For starters, a constant increase in heart rate by drugs such as cigarette smoking can cause heart disease, (WHO).

According to the World Health Organization, tobacco use leads to diseases impacting the heart and lungs, such as heart attacks, strokes, chronic obstructive pulmonary disease (COPD), emphysema, and cancer. Most cigarette elicited cancers are lung cancer, cancers of the larynx, mouth, and pancreas. Cigarette smoke also causes myocardial infarctions, peripheral vascular disease and hypertension. The world Health Organization estimates that tobacco accounts for about 5. 4 million fatalities in 2004 and about 100 million fatalities during the 20th century.

In addition to its habit forming effects on the central nervous system, cigarette smoke contains a multitude of cancer-causing agents. They work by executed to DNA causing many ancestral mutations. Cigarette smoking could be the main perpetrator that is doing the executed to DNA causing ancestral mutations, that leads to cancer. Cigarette smoking is asked break up the natural processes of apoptosis (programmed cell death) by executed to DNA in cells, (National Institute of Health (NIH)). Flawed cells consist of junk DNA and other squander. When apoptosis is inhibited, natural cell death does not occur; instead, flawed cells are allowed to proliferate or grow larger, uncontrollably. It’s this that happens in cancer and the main reason why cigarette smokers are more susceptible to developing cancers.

When apoptosis is uncontrollably triggered by chemicals, such as cigarette smoking, it causes normal cells to die off. This may be what is happening in the heart tissue of cigarette smokers who suffer from heart disease and may be what is taking place in the extremities of cigarette smokers, who often complain of excessive coldness in their fingertips, arms, toes, and legs, where circulation is lowest.

There are no existing studies to support this exact explanation. However, based on the information about known scientific proof of apoptosis and the increase in death rates of cigarette smokers, this hypothetical explanation has some credence; and will continue to have credence until proven otherwise! There is something lethal that is happening to cigarette smokers and cigarette smoking is one of the agents behind it.

The tar in cigarette smoke is also a realtor that sucks the life span out of cigarette smokers. The lung of a cigarette smoker is usually as black as the color of asphalt. It is like a severe little bit of burned pot beef roasts. This is why most cigarette smokers have difficulty breathing. It is difficult for air to pass freely down the air tract of smokers. The sad thing is that it is difficult for cigarette smokers to quit. So, they continue down the road of break down, day after day, puffing on the silent killer–cigarette smoking.

One very important solution to quitting smoking is smoking one less cigarette a day or even one less cigarette in a month if one less cigarette a day is too steep of an adjustment to the lethal habit. If one normally buds a pack of smoking cigarettes a day, that individual should remove one of those smoking cigarettes and toss it–throw it in the garbage can. Remember that the smoking of smoking cigarettes started gradually. No one started smoking a pack of smoking cigarettes a day in that awful beginning stage of cigarettes. Smoking one less cigarette per a particular time frame will help eliminate the excessive cholinergic receptors that cigarette smoking so dearly craves.

Wellbutrin is another method for helping people quit smoking. Wellbutrin is an antidepressant drug as used by people with depression. However, it is very potent in assisting people kick the lethal habit of smoking. It can be taken while smoking, unlike other smoking cessation agents. Wellbutrin blocks cigarette smoking receptors and weakens the action of dopamine reuptake by neurons, (J Pharmacol Exp Ther. 2000 March; 295(1): 321-7. ).

Cigarette smokers who are interested in quitting should implement an exercise program in their schedule because the lack of cigarette smoking in ex-cigarette smokers causes weight-gain. How do we know this? Former cigarette smokers who kicked the habit complain of putting on weight after they quit smoking. Ask any ex-cigarette smoker. One will hear the same principle. Cigarette smoking induces weight-loss in smokers. This is why most cigarette smokers are slim or slim. If a cigarette smoker is overweight while cigarettes, then that person may want to seek medical assistance because there will probably be a very dangerous sickness lurking in the shadows.